GlyT1


Elevation of extracellular synaptic glycine concentration by blockade of GlyT1 has been hypothesized to potentiate NMDA receptor function in vivo and to represent a rational approach for the treatment of schizophrenia and cognitive disorders.
  • NVP CXCR2 20 EI1973

    NVP CXCR2 20是活性选择性 CXCR2 拮抗剂。

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  • LY 2365109 hydrochloride EI1589

    LY 2365109 hydrochloride是活性选择性 GlyT1 抑制剂。

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  • IT1t dihydrochloride EI1372

    IT1t dihydrochloride是活性的 CXCR4 拮抗剂。

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  • NLG919 EY1350

    NLG919是一种新型有效的indoleamine-2,3-dioxygenase (IDO)(吲哚胺-2,3-双加氧酶)抑制剂,EC50为75 nM。

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  • Crizotinib EY1172

    Crizotinib (PF-02341066)是一种有效的c-Met抑制剂,作用于人的c-Met激酶时,Ki为4 nM。

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